This document provides an overview of the muscular system. It discusses the three types of muscles - skeletal, cardiac, and smooth muscles. Skeletal muscles are voluntary and striated, found attached to bones, and enable movement. Cardiac muscle is exclusively found in the heart and contracts involuntarily. Smooth muscles are not striated, act involuntarily, and are located in organs like the intestines. The document also examines muscle structure, types of contractions, energy sources, exercise effects, and attachments. Examples of major skeletal muscles and their functions are outlined.
1. Presented by: Mr.Vijay Salvekar
Associate Professor
Dept. of Pharmacology
GRY Institute of Pharmacy , Borawan
Muscular
System
2. Did you know that ?
- more than 50% of body weight
is muscle !
- And muscle is made up of
proteins and water
3.
4. The Muscular System
• Muscles are responsible for all movement
of the body
• There are three basic types of muscle
– Skeletal
– Cardiac
– Smooth
5. Info About Muscles
• Only body tissue able
to contract
• create movement by
flexing and extending
joints
• Body energy
converters (many
muscle cells contain
many mitochondria)
8. Classification of Muscle
Skeletal-
found in limbs
Cardiac-
found in heart
Smooth-
Found in
viscera
Striated, multi-
nucleated
Striated, 1
nucleus
Not striated, 1
nucleus
voluntary involuntary involuntary
9. Characteristics of Muscle
• Skeletal and smooth muscle are elongated
• Muscle cell = muscle fiber
• Contraction of a muscle is due to movement
of microfilaments (protein fibers)
• All muscles share some terminology
– Prefixes myo and mys refer to muscle
– Prefix sarco refers to flesh
10. Shapes of Muscles
• Triangular- shoulder, neck
• Spindle- arms, legs
• Flat- diaphragm, forehead
• Circular- mouth, anus
11. Skeletal Muscle
• Most are attached by tendons to bones
• Cells have more than one nucleus
(multinucleated)
• Striated- have stripes, banding
• Voluntary- subject to conscious control
• Tendons are mostly made of collagen fibers
• Found in the limbs
• Produce movement, maintain posture,
generate heat, stabilize joints
12. Structure of skeletal muscle
• Each cell (fibre) is long and cylindrical
• Muscle fibres are multi-nucleated
• Typically 50-60mm in diameter, and up
to 10cm long
• The contractile elements of
skeletal muscle cells are
myofibrils
13. Skeletal muscle - Summary
• Voluntary movement
of skeletal parts
• Spans joints and
attached to skeleton
• Multi-nucleated,
striated, cylindrical
fibres
14. Smooth Muscle
• No striations
• Spindle shaped
• Single nucleus
• Involuntary- no conscious control
• Found mainly in the walls of hollow organs
15. Smooth muscle
• Lines walls of viscera
• Found in longitudinal or
circular arrangement
• Alternate contraction of
circular & longitudinal
muscle in the intestine
leads to peristalsis
16. Structure of smooth muscle
• Spindle shaped uni-nucleated cells
• Striations not observed
• Actin and myosin filaments are present(
protein fibers)
17. Smooth muscle - Summary
• Found in walls of
hollow internal
organs
• Involuntary
movement of
internal organs
• Elongated, spindle
shaped fibre with
single nucleus
18. Cardiac Muscle
• Striations
• Branching cells
• Involuntary
• Found only in the heart
• Usually has a single nucleus, but can have
more than one
19. Cardiac muscle
• Main muscle of heart
• Pumping mass of heart
• Critical in humans
• Heart muscle cells
behave as one unit
• Heart always contracts
to it’s full extent
20. Structure of cardiac muscle
• Cardiac muscle cells (fibres) are
short, branched and interconnected
• Cells are striated & usually have 1
nucleus
• Adjacent cardiac cells are joined
via electrical synapses (gap
junctions)
• These gap junctions appear as
dark lines and are called
intercalated discs
21. Cardiac muscle - Summary
• Found in the heart
• Involuntary rhythmic
contraction
• Branched, striated
fibre with single
nucleus and
intercalated discs
22. Muscle Control
Type of
muscle
Nervous
control
Type of
control
Example
Skeletal
Skeletal Controlled
by CNS
Voluntary Lifting a
glass
Cardiac Regulated
by ANS
Involuntary Heart
beating
Smooth Controlled
by ANS
Involuntary Peristalsis
23. Types of Responses
• Twitch-
– A single brief contraction
– Not a normal muscle function
• Tetanus
– One contraction immediately followed by
another
– Muscle never completely returns to a relaxed
state
– Effects are compounded
24. Where Does the Energy Come
From?
• Energy is stored in the muscles in the form
of ATP
• ATP comes from the breakdown of glucose
during Cellular Respiration
• This all happens in the Mitochondria of the
cell
• When a muscle is fatigued (tired) it is
unable to contract because of lack of
Oxygen
25. Exercise and Muscles
• Isotonic- muscles shorten and movement
occurs ( most normal exercise)
• Isometric- tension in muscles increases, no
movement occurs (pushing one hand against
the other)
26. How are Muscles Attached to
Bone?
• Origin-attachment to a movable bone
• Insertion- attachment to an immovable
bone
• Muscles are always attached to at least 2
points
• Movement is attained due to a muscle
moving an attached bone
28. The Skeletal Muscles
There are about 650 muscles in the
human body. They enable us to
move, maintain posture and generate
heat. In this section we will only
study a sample of the major muscles.