Symptoms of Immune Thrombocytopenia

immune-thrombocytopenic-purpura-skin condition
One symptom of ITP is tiny red dots under the skin that are a result of very small bleeds.Adobe Stock
Immune thrombocytopenia, also called ITP, is a disorder of the blood in which there is a shortage of platelets, or blood cells that are responsible for normal clotting, according to MedlinePlus.

 As a result of this shortage, blood does not clot as it should.
In a healthy person, platelets clump together to seal off cuts and injuries to blood vessels, according to the Cleveland Clinic.

 But when platelet levels are too low, bleeding can occur both internally and externally.
There are two types of ITP: acute ITP, which is short-term, and chronic ITP. Acute ITP is the more common type and mainly happens in children who have had a recent viral infection.

 It usually lasts no more than six months.
Chronic ITP is mostly seen in adults and lasts beyond six months.

 It is thought to be caused by an autoimmune response in which your own immune system turns on itself and destroys platelets when it is not supposed to. Doctors have yet to figure out why this happens.

7 Signs and Symptoms of ITP

ITP can occur with no symptoms, but these are the ones to look out for.
7 Signs and Symptoms of ITP

Signs You May Have ITP

In some cases, ITP can occur with no symptoms, according to the Mayo Clinic.

Symptoms may begin to appear when platelet levels are very low. According to the National Organization for Rare Disorders (NORD), symptoms of ITP can include:

  • Bruising or purple spots on the skin that occur very easily or for no known reason. These bruises are called purpura and may also appear in the mouth.
  • Small red dots that resemble a rash. These dots, called petechiae, are actually caused by bleeding underneath the skin as a result of damage to blood vessels or leaks in a capillary wall.
  • Frequent nosebleeds that are difficult to stop.
  • Bleeding from the gums
  • Unusually long menstrual cycle or heavy menstrual bleeding
  • Hematoma, or a pooling of clotted or partially clotted blood under the skin. A hematoma can cause pain and swelling.
  • Blood in urine, stool, or vomit

Mental Health Effects of ITP

According to the Platelet Disorder Support Association (PDSA), the excessive bleeding that comes with ITP can lead to anemia, a condition characterized by low levels of red blood cells. In people with anemia, there aren’t enough healthy red blood cells to carry adequate oxygen to the body’s tissues. This often results in extreme fatigue and low energy levels.

Mental health issues such as depression and anxiety are also common in people with ITP, the PDSA reports. This can lead to social anxiety and difficulties concentrating at work or school. It’s not known whether these are symptoms of the disease itself, the result of anxiety, or side effects of medication.

Symptoms of Brain Bleeds

In rare cases, ITP can lead to a brain bleed, or intracranial hemorrhage, according to NORD.

According to the Cleveland Clinic, symptoms of brain bleeds may include:

  • Sudden numbness, weakness, or paralysis in the face, arm, or leg, especially if it is on one side of the body
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Confusion
  • Difficulty swallowing
  • Trouble seeing or loss of vision
  • Slurred speech
  • Loss of balance
  • Seizures
  • Sensitivity to light
  • Stiff neck
  • Trouble reading, writing, or understanding speech
  • Difficulty breathing
  • Loss of consciousness

An intracranial hemorrhage is a medical emergency and can be fatal. If you or a loved one experiences these symptoms, it is important to get to your local emergency room immediately.

Editorial Sources and Fact-Checking

Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.

Sources

  1. Immune Thrombocytopenia. Medline Plus.
  2. Immune Thrombocytopenia. Cleveland Clinic.
  3. Immune Thrombocytopenia (ITP): Symptoms and Causes. Mayo Clinic.
  4. Immune Thrombocytopenia. National Organization for Rare Disorders.
  5. Brain Bleed, Hemorrhage (Intracranial Hemorrhage). Cleveland Clinic.

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